Gabaar
Targeting GABAAR-Associated Proteins: New Modulators ... - Frontiers
www.frontiersin.org
Jun 12, 2019 ... γ-aminobutyric acid type A receptors (GABAARs) are the major mediators of synaptic inhibition in the brain. Aberrant GABAAR activity or ...
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis ...
pubs.rsc.org
Enterotoxigenic Escherichia coli (ETEC) triggers diarrhea in humans and livestock. We have previously showed that ETEC promotes intestinal epithelial cell ...
γ2 GABAAR Trafficking and the Consequences of Human ... - Frontiers
www.frontiersin.org
Aug 2, 2018 ... GABAARs are ligand-gated ionotropic chloride (Cl-) channels ubiquitously expressed throughout the CNS that play a fundamental role in ...
Effects of the Selective α5-GABAAR Antagonist S44819 on ...
www.jneurosci.org
Dec 7, 2016 ... Alpha-5 gamma-aminobutyric acid type A receptors (α5-GABAARs) are located extrasynaptically, regulate neuronal excitability through tonic ...
Compromising the phosphodependent regulation of the GABAAR β3 ...
www.pnas.org
SignificanceAlterations in the efficacy of neuronal inhibition mediated by GABAA receptors (GABAARs) containing β3 subunits are continually implicated in ...
Role of GABAAR trafficking in the plasticity of inhibitory synapses ...
onlinelibrary.wiley.com
Jul 18, 2016 ... Abstract Neuronal excitability depends on the balance between inhibitory and excitatory neurotransmission, which in the CNS are mainly ...
female epilepsy protein PCDH19 is a new GABAAR-binding partner ...
academic.oup.com
Abstract. The PCDH19 gene (Xp22.1) encodes the cell-adhesion protein protocadherin-19 (PCDH19) and is responsible for a neurodevelopmental pathology ...
Anesthetic Propofol Promotes Tumor Metastasis in Lungs via ...
onlinelibrary.wiley.com
Jul 15, 2021 ... Abstract Generation of circulating tumor cells (CTCs), a key step in tumor metastasis, occurs during surgical tumor resection, ...
γ2 GABAAR Trafficking and the Consequences of Human Genetic ...
www.ncbi.nlm.nih.gov
Aug 23, 2018 ... Here, we introduce in vitro and in vivo findings regarding the specific role of the γ2 subunit in receptor trafficking. We then examine γ2 ...
Gephyrin-Independent GABAAR Mobility and Clustering during ...
journals.plos.org
Apr 26, 2012 ... The activity-dependent modulation of GABA-A receptor (GABAAR) clustering at synapses controls inhibitory synaptic transmission.